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APD

Automated peritoneal dialysis with sleep•safe harmony and SILENCIA

As individual as your patient - Automated peritoneal dialysis with sleep•safe harmony

The prescribing information for Peritoneal Dialysis solutions can be viewed here. 

Why automated peritoneal dialysis (APD)?

APD uses a programmable machine, or cycler, that controls the volume, filling, dwell time and drainage of the solution. Thanks to automated dialysis, patients can be dialysed at home, even when sleeping.

As APD is offering more free daytime, it is a PD technique with obvious advantages for patient’s lifestyle. Patients may pursue a job and have more time for personal and family activities.1

Finally, APD cyclers offer a variety of individualisation options for the treatment, allowing you to even better consider the needs of your patient, supporting you to improve patient care.

In APD both our cyclers, sleep•safe harmony and SILENCIA, offer advanced features, all aimed at improving patient care.

In APD our sleep•safe harmony cycler offers advanced features, all aimed at improving patient care.

  • Increased treatment flexibility with FlexPoint technology2
  • Integrated on-screen animations give guidance and facilitate setup2
  • As proposed by Fischbach et al., potentially improved ultrafiltration (UF) as well as clearance of urea, creatinine, phosphate, and sodium, with individually adapted APD (aAPD)3
  • Advanced fluid management information package available as fluid management aims to better control the patient’s fluid status in order to improve longterm technique and patient survival4

Getting started with education in APD – The difficult part was making it easier

FMC created training solutions that focus on conveying the information that really matter and offers support in preparing and setting up the treatment.

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Preparation

Train

  • Training videos for caregivers and patients to support training
  • Start with supportive extra training material for our APD devices
  • Set of patient information materials to support you in training the patient

Start

  • Support in planning and preparing the therapeutic home environment

Our products - Key features of the sleep·safe harmony

sleep·safe harmony offers features aimed at improving patient care. It also provides training support by guiding on-screen animations directly on the device.

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Adapted APD (aAPD) is one way to personalize treatments

 

sleep•safe harmony offers multiple options to invidualise prescriptions according to patient’s needs.

 

Using sleep•safe harmony, the prescription can be individualised on several levels:

  • Infusion volume
  • Dwell time
  • Glucose profile
  • Calcium profile
  • Different solutions per cycle within the same treatment
  • FlexPoint

Because every patient is different: aAPD – Fischbach et al.2 suggests potential better ultrafiltration and clearance within a 9 hour treatment totalling 12000ml fill volume, in comparison to CAPD, .2

Your patients have a chronic disease in common, but differ in many ways: age, height, weight, stage of illness, residual kidney function etc. These differences have a decision impact on the PD treatment required. 
Patients’ needs are different:

Fischbach study supports aAPD2

Fischbach M. et al. conducted a randomised, prospective, cross-over, multicenter study. Nineteen patients were included in the final analysis.

According to Fischbach et al., aAPD offers better results using the same time and resources2

  • aAPD is possible without extra fluids or a longer amount of time
  • Efficiently uses existing treatment resources: better ultrafiltration and clearance with same 1.5% glucose Peritoneal Dialysis solution, 12000ml fluid volume and 9 hour treatment time compared to conventional APD (cAPD)
Our products - Key features of SILENCIA

A representation of the aAPD method described by Fischbach M. et al., (2011)

 

Attaining adequacy targets

The aAPD approach was proposed by Fischbach M. et al.2 By combining sequences of short dwells and small fill volumes with long dwells and large fill volumes, aAPD aims to promote UF and clearance within one PD session. The blood purification and UF achieved for every gram of glucose absorbed was higher in aAPD in comparison to cAPD.

The challenges of PD – Reaching adequacy targets

Reaching adequacy targets in PD for both UF and clearance is challenging. Fischbach et al. propose that shorter dwell times and smaller fill volumes promote the process of UF, while longer dwell times and large fill volumes increase solute clearance.2 The proposed strategy may have the potential to improve the two targets within one PD session.

cAPD

aAPD

Figure 1: Modified cAPD graphic following Fischbach M. et al.

Figure 1: Modified cAPD graphic following Fischbach M. et al. 2011

aAPD

Figure 2: Modified aAPD graphic following Fischbach M. et al.

 

Figure 2: Modified aAPD graphic following Fischbach M. et al. 2011

 

Adapted APD is possible without extra fluids or a longer amount of time, with the same glucose concentration.

Summary of potential patient benefits as reported by Fischbach et al2

Patient benefits

  • Improves ultrafiltration
  • Better sodium removal
  • Lower blood pressure
  • Promotes clearance: urea, creatinine, phosphate
  • Reduced metabolic load
     

Clinical value

  • Improved use of existing treatment resources: better ultrafiltration and clearance with same 1.5% glucose Peritoneal Dialysis solution, 12000ml fluid volume and 9 hour treatment time compared to cAPD

APD monitoring and support

Smart digital tools offer convenience for patients and caregivers in the comfort of the patients’ homes.

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Treatment

Support

  • A simple ordering process in combination with personal phone support ensures that patients can order materials anytime and anywhere
  • The delivery service ensures that PD solutions and disposables are delivered straight to your patient’s doorstep
  • The PD travel service enables patients to continue travelling as the required goods are directly sent to the patient’s holiday destination*

Monitor

  • Streamlined PD therapy management through easy accessibility to therapy information via our PatientOnLine tool

* The service is not available in all countries. The availability of the service and products must be clarified before planning or booking a vacation.

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