Estimated dialysate and water savings with HVHDF

In this Research in Brief, Linda Ficociello, DSc, Vice President, Real-World Evidence Generation, Renal Research Institute (RRI), discusses dialysate savings when transitioning patients from hemodialysis (HD) to high-volume hemodiafiltration (HVHDF). In this project, she and her team compared HVHDF treatments to HD treatments, focusing on dialysate flow rates and treatment time to compare dialysate savings before and after the conversion to HVHDF.

Although adequacy and treatment time were similar in HD and HVHDF treatments, they found that the dialysate flow rates were lower in HVHDF. This resulted in about a 43-liter decrease in dialysate when comparing HVHDF to HD, which, once adjusted for the average substitution volume, resulted in approximately 19 liters per treatment in savings in dialysate compared to conventional hemodialysis.

To learn more, read the full abstract in the Journal of the American Society of Nephrology: Estimated Dialysate and Water Savings in a US Dialysis Clinic Initiating High-Volume Hemodiafiltration.

Watch the full Research in Brief below: